Effects of emotional labor on musculoskeletal disorders among physical therapists in Seoul

Introduction: Healthcare workers, including physical therapists, have some of the most important roles in the healthcare system, as observed during the coronavirus disease 2019 pandemic. Physical therapists encounter emotionally and physically vulnerable patients, experience emotional labor, and are exposed to conditions that can lead to job stress and musculoskeletal disorders. We aimed to examine the relationships between physical therapists' emotional labor, its effect on perceived job stress, and the risk of developing musculoskeletal disorders. Methods: We conducted a 30-day survey among 230 physical therapists working in various settings from October 2 to November 1, 2019. Questionnaires, including questions on musculoskeletal symptoms, perceived job stress, and emotional labor, were administered to the participants. Results: The emotional labor sub-factors "overload and conflict in customer service" (β=0.201, p>0.001), "emotional inconsistency and impairment" (β=0.199, p>0.001), and "organizational support and protection system" (β=0.298, p>0.001) affected the job stress sub-factors "physical environment" (β=0.105, p>0.020), "insufficient compensation" (β=0.072, p<0.05), and "relational conflict" (β=-0.083, p>0.024). These job stress sub-factors affected musculoskeletal disorders. Conclusion: To prevent the long-term consequences of work-related strain, physical therapists should receive support for maintaining a healthy lifestyle and developing effective methods of communication with patients. Encouragement of activities for psychological rejuvenation and sharing emotional difficulties with colleagues is also desirable. Moreover, it is necessary to establish a direct line of grievance communication between physical therapists to hospitals. © 2023 The Author(s).

A Study on the Economic Resilience of Industrial Parks

The development of globalization has brought about obvious differences in the resilience of different regions against economic crises. Regional economic resilience refers to the ability of a region's economy to resist shocks when faced with external disturbances or to break away from its existing growth model in favor of a better path, Resilience represents the region's adaptability, innovation, and sustainability. This paper describes an empirical analysis on the 60 designated industrial park developments under the Industrial Development Bureau in Taiwan. Over a period of short-term disturbances, the industrial parks are analyzed from four aspects: industrial structure, regional development foundation, enterprise competitiveness and labor conditions, and government governance and policy systems. Through discriminant analysis, we analyze the characteristics of factors that mainly affect the economic resilience of 60 industrial parks faced with shocks such as the subprime mortgage crisis in 2008, the five-day work week in 2016, and the COVID-19 outbreak in 2019. We found that industrial structure, specifically diversified industrial structure, is the major factor behind enhanced regional economic resilience. If the scale of specialized industries is large enough, they can form sufficient capacity to resist external changes and also be economically resilient. Under the negative impact, the amount of innovation can be an important part of post-disaster recovery, and stable innovation input will become a main factor for the sustainable development of industrial parks. The pressure of the uncertainty of global economic development and the transformation and upgrading of the domestic economy underscore that enterprises urgently need automation and digital transformation to enhance their competitiveness. In order to enhance economic resilience to adapt to changes in the overall environment, the industrial parks need to adjust adaptively, improve their industrial structure, and promote innovation, hoping that the regional economy will move towards a more stable and sustainable development path. © 2023 by the authors.

3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists

Toll-like receptor 7 (TLR7) is an attractive target for developing immune modulators to enhance innate immunity against ssRNA virus infections, including hepatitis C and COVID-19. Ten 3-(5-hydroxyphenyl)-5-phenyl-2-pyrazolines were tested using TLR7 reporter cells, overexpressing TLR7 and the NF-B-inducible SEAP reporter gene to discover a novel TLR7 agonist enhancing innate immunity. Of these, 2-(3-(2-hydroxynaphthalen-1-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one (compound 6) showed the best TLR7 agonistic activity, and further experiments were carried out to study the immune-modulatory capability of compound 6. Treatment with compound 6 rapidly induced phosphorylation of IRAK4, IKKα/β, IBα, and p65/RelA in THP1 monocytic cells. In addition, it increased the expression of NF-B-regulated innate cytokines, such as TNFα and IL1β, in THP1 monocytic cells. These data suggest that compound 6 induces an innate immune response by agonizing TLR7 activity in THP1 human monocytic cells. Therefore, compound 6 can be used as an innate immune modulator to develop antiviral agents and vaccine adjuvants. © 2023 Ji Hwan Kim et al.

Dissecting returns of non-fungible tokens (NFTs): Evidence from CryptoPunks

We use transaction data on CryptoPunks to dissect the factors affecting the returns of non-fungible tokens (NFTs). Our results show that trading volume in the short period before a trader buys (sells) CryptoPunk relates negatively (positively) to the returns on NFTs, suggesting that when market trading volume is at a high level, NFT owners are better off on the sell side, and investors interested in NFTs should avoid joining the herd. Turnover of a token tends to harm its returns. Finally, both traders' willingness to purchase and trading experience have a positive impact on NFT returns within short-term investment horizons. © 2023 Elsevier Inc.

Learning-Based Personal Speech Enhancement for Teleconferencing by Exploiting Spatial-Spectral Features

Teleconferencing is becoming essential during the COVID-19 pandemic. However, in real-world applications, speech quality can deteriorate due to, for example, background interference, noise, or reverberation. To solve this problem, target speech extraction from the mixture signals can be performed with the aid of the user's vocal features. Various features are accounted for in this study's proposed system, including speaker embeddings derived from user enrollment and a novel long-short-term spatial coherence (LSTSC) feature pertaining to the target speaker activity. As a learning-based approach, a target speech sifting network was employed to extract the target signal. The network trained with LSTSC in the proposed approach is robust to microphone array geometries and the number of microphones. Furthermore, the proposed enhancement system was compared with a baseline system with speaker embeddings and interchannel phase difference. The results demonstrated the superior performance of the proposed system over the baseline in enhancement performance and robustness.

Corporeality, Genetic Technology, and Climate Change in the Year of the Flood

In her novel The Year of the Flood, Margaret Atwood vividly illustrates the unmistakable impact of climate change on people's lives these days. Genetic manipulation has become one of the technologies that people have grown dependent on to solve environmental problems in this age of climate change, where severe droughts, rising sea levels, melting glaciers, and the like are being reported more frequently than ever. But genetic engineering has profound consequences for human corporealities, as both COVID-19 and The Year of the Flood show. In the novel, Atwood presents a world where humanity finds it hardly possible to survive without genetic fiddling. We find ourselves in a similar situation in real life, especially during the current COVID-19 pandemic where genetic alteration technology is essential: studies have shown that vaccination using genetic engineering is the best way to halt the spread of the virus, but no one can give a definite answer to its long-term effects on bodies. Atwood illustrates through the Paradice Project episode in the novel that such a genetic experiment can make the ecological future more uncertain and unstable in the age of climate crisis. Though a few monopolistic multinational GMO companies touted genetic engineering technologies as a benevolent solution, it has become evident that they are only doing so for their own profit, as exemplified by the Vitamin pill episode in the novel.. In the real world and in The Year of the Flood, climate change and multinational capitalism exert a bad influence on biodiversity. With human and nonhuman animal bodies being mistreated more than ever as materials for the gene industry, Atwood shows how badly women are exploited in an age of genetic engineering. As we depend too much on genetic technologies, we tend to overlook the small but influential agencies within human and nonhuman assemblages, which result in dismissing the entanglement between human and nonhuman beings. It is becoming more and more difficult to imagine how we can function without genetic alteration, especially during the COVID-19 pandemic.

Efficacy in COVID-19 management: the case of ASEAN

Purpose: The effects of the COVID-19 pandemic have been devastating to countries around the world. Much of the problem has been the need to contain the infection via harsh social movement restrictions while having the necessary policies to cushion the ensuing economic blows that follow them. This study aims to look at The Association of Southeast Asian Nations (ASEAN) countries and assess the good practices that are associated with those which performed relatively better than the rest. Design/methodology/approach: The authors use data envelopment analysis (DEA) to identify the most efficient country among the ASEAN nations in dealing with the pandemic and observe their practices with regard to the movement control metrics. Findings: One particular country stood out in this regard, which is Singapore. The authors observed that its social restrictions were less stringent than many others yet its management of the pandemic has been highly successful despite having had the highest number of cases at one stage in 2020. This suggests massive lockdowns may not necessarily be the solution. However, the nation did place a high priority in having a high-income support, effective public campaigning and very restrictive policy on public events. In terms of originality and value, this paper uses DEA in identifying the best practice among ASEAN countries in dealing with the pandemic, both from an economic and medical perspectives. Originality/value: To the best of the authors’ knowledge, no other papers have used this approach. The authors hope the findings can be of some value to policymakers in designing better (public) policies when it comes to dealing with pandemics in the future. © 2022, Emerald Publishing Limited.

Delphi Survey for COVID-19 Vaccination in Korean Children Between 5 and 11 Years Old

Purpose: During the coronavirus disease 2019 (COVID-19) pandemic, we conducted a Delphi survey that included the experts from the field of COVID-19 immunization in children aged 5–11 years. The aim was to organize collective expert opinions on COVID-19 vaccination in young children in the Republic of Korea, and so thus assist the vaccination policy. Methods: The panels included pediatric infectious disease specialists, preventive medicine experts, infectious disease physicians, and COVID-19 vaccine experts consulting the Ministry of Health and Welfare. The Delphi survey was conducted online using a questionnaire from February 14 to February 27, 2022. Results: The Delphi panels agreed that children were vulnerable to COVID-19, and the severity of illness was modest. Furthermore the panels reported that children with chronic illness were more susceptible to a worsening clinical course. There were generally positive opinions on the effectiveness of COVID-19 vaccination in children aged 5–11 years, and experts gathered a slightly positive opinion that the adverse events of pediatric COVID-19 were not numerous. The benefits of COVID-19 vaccination were evaluated at a level similar to the potential risks in children. Currently, the only approved mRNA platform vaccine in children seemed to be sustainable;however, the recombinant protein platform COVID-19 vaccines were evaluated as better options. Conclusions: Due to the surge of the Omicron variant and an increase in pediatric cases, the COVID-19 vaccination in young children may have to be considered. Panels had neutral opinions regarding the COVID-19 vaccination in children aged 5–11 years. Thus monitoring of the epidemiology and the data about the safety of COVID-19 vaccination should be continued.

How can an economic scenario generation model cope with abrupt changes in financial markets?

Purpose - It is quite possible that financial institutions including life insurance companies would encounter turbulent situations such as the COVID-19 pandemic before policies mature. Constructing models that can generate scenarios for major assets to cover abrupt changes in financial markets is thus essential for the financial institution's risk management. Design/methodology/approach - The key issues in such modeling include how to manage the large number of risk factors involved, how to model the dynamics of chosen or derived factors and how to incorporate relations among these factors. The authors propose the orthogonal ARMA-GARCH (autoregressive movingaverage-generalized autoregressive conditional heteroskedasticity) approach to tackle these issues. The constructed economic scenario generation (ESG) models pass the backtests covering the period from the beginning of 2018 to the end of May 2020, which includes the turbulent situations caused by COVID-19. Findings - The backtesting covering the turbulent period of COVID-19, along with fan charts and comparisons on simulated and historical statistics, validates our approach. Originality/value - This paper is the first one that attempts to generate complex long-term economic scenarios for a large-scale portfolio from its large dimensional covariance matrix estimated by the orthogonal ARMA-GARCH model.

Noncontact Sensing of Contagion.

The World Health Organization (WHO) has declared COVID-19 a pandemic. We review and reduce the clinical literature on diagnosis of COVID-19 through symptoms that might be remotely detected as of early May 2020. Vital signs associated with respiratory distress and fever, coughing, and visible infections have been reported. Fever screening by temperature monitoring is currently popular. However, improved noncontact detection is sought. Vital signs including heart rate and respiratory rate are affected by the condition. Cough, fatigue, and visible infections are also reported as common symptoms. There are non-contact methods for measuring vital signs remotely that have been shown to have acceptable accuracy, reliability, and practicality in some settings. Each has its pros and cons and may perform well in some challenges but be inadequate in others. Our review shows that visible spectrum and thermal spectrum cameras offer the best options for truly noncontact sensing of those studied to date, thermal cameras due to their potential to measure all likely symptoms on a single camera, especially temperature, and video cameras due to their availability, cost, adaptability, and compatibility. Substantial supply chain disruptions during the pandemic and the widespread nature of the problem means that cost-effectiveness and availability are important considerations.

Clinical Presentation and Outcomes of Middle East Respiratory Syndrome in the Republic of Korea

Background: From May to July 2015, the Republic of Korea experienced the largest outbreak of Middle East respiratory syndrome (MERS) outside the Arabian Peninsula. A total of 186 patients, including 36 deaths, had been diagnosed with MERS-coronavirus (MERS-CoV) infection as of September 30th, 2015. Materials and Methods: We obtained information of patients who were confirmed to have MERS-CoV infection. MERS-CoV infection was diagnosed using real-time reverse-transcriptase polymerase chain reaction assay. Results: The median age of the patients was 55 years (range, 16 to 86). A total of 55.4% of the patients had one or more coexisting medical conditions. The most common symptom was fever (95.2%). At admission, leukopenia (42.6%), thrombocytopenia (46.6%), and elevation of aspartate aminotransferase (42.7%) were observed. Pneumonia was detected in 68.3% of patients at admission and developed in 80.8% during the disease course. Antiviral agents were used for 74.7% of patients. Mechanical ventilation, extracorporeal membrane oxygenation, and convalescent serum were employed for 24.5%, 7.1%, and 3.8% of patients, respectively. Older age, presence of coexisting medical conditions including diabetes or chronic lung disease, presence of dyspnea, hypotension, and leukocytosis at admission, and the use of mechanical ventilation were revealed to be independent predictors of death. Conclusion: The clinical features of MERS-CoV infection in the Republic of Korea were similar to those of previous outbreaks in the Middle East. However, the overall mortality rate (20.4%) was lower than that in previous reports. Enhanced surveillance and active management of patients during the outbreak may have resulted in improved outcomes. FAU - Choi, Won Suk